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Sleep Medicine

A practical collection of sleep physiology, sleep-disordered breathing, diagnostic testing, PAP therapy, insomnia, circadian biology, and emerging concepts in precision sleep medicine.

Sleep Medicine Topics

Explore each topic through a recent review or authoritative evidence synthesis.

Sleep Physiology

Sleep architecture, REM and NREM physiology, autonomic changes, ventilatory control, and neurobiology of sleep.

Recent physiology review →

Obstructive Sleep Apnea

Pathophysiology, endotypes, phenotypes, cardiovascular consequences, REM-predominant disease, and treatment selection.

Recent endotype review →

Sleep Testing

Polysomnography, HSAT, WatchPAT, AHI definitions, oxygen metrics, pretest probability, and interpretation pitfalls.

Recent diagnostic guidance →

PAP Therapy

CPAP, APAP, bilevel therapy, pressure selection, adherence, troubleshooting, and treatment-response assessment.

Recent PAP review →

Insomnia & Circadian Disorders

CBT-I, sleep scheduling, circadian timing, behavioral assessment, and practical treatment principles.

Recent COMISA review →

Hypersomnia & Emerging Concepts

Excessive sleepiness, central hypersomnolence disorders, pharmacotherapy, biomarkers, and precision approaches.

Recent hypersomnolence review →

Featured Sleep Teaching

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Article / Review

OSA is not one disease — it is a collection of physiologic failure modes

The same apnea-hypopnea index can emerge from very different combinations of airway anatomy, ventilatory control, arousal biology, and upper-airway muscle performance.

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