https://aliaraghimd.org/2026/10/06/premature-closure-is-often-a-failure-to-reopen-the-case-when-new-data-no-longer-fit/Ali Araghi, MDen2026-10-06T15:32:30+00:00Premature closure is often a failure to reopen the case when new data no longer fitDiagnostic Reasoning, Diagnostic Errorhttps://aliaraghimd.org/2026/10/06/a-diagnostic-test-only-helps-when-it-meaningfully-changes-probability/Ali Araghi, MDen2026-10-06T15:32:26+00:00A diagnostic test only helps when it meaningfully changes probabilityDiagnostic Reasoning, Bayesian Reasoninghttps://aliaraghimd.org/2026/10/06/a-good-problem-representation-is-often-more-valuable-than-a-long-differential/Ali Araghi, MDen2026-10-06T15:32:22+00:00A good problem representation is often more valuable than a long differentialDiagnostic Reasoning, Problem Representation, Illness Scriptshttps://aliaraghimd.org/2026/10/06/clinical-reasoning-is-not-a-checklist-it-is-a-process-of-updating-probabilities/Ali Araghi, MDen2026-10-06T15:32:18+00:00Clinical reasoning is not a checklist — it is a process of updating probabilitiesDiagnostic Reasoning, Problem Representation, Bayesian Reasoning, Illness Scriptshttps://aliaraghimd.org/2026/10/06/stopping-obesity-medication-often-removes-the-biologic-support-that-maintained-the-weight-loss/Ali Araghi, MDen2026-10-06T15:08:27+00:00Stopping obesity medication often removes the biologic support that maintained the weight lossObesity Pharmacotherapy, Chronic Obesity Biologyhttps://aliaraghimd.org/2026/10/06/protein-protects-more-than-muscle-during-weight-loss/Ali Araghi, MDen2026-10-06T15:08:24+00:00Protein protects more than muscle during weight lossNutrition, Exercise Physiology, Protein and Lean Masshttps://aliaraghimd.org/2026/10/06/weight-loss-lowers-energy-expenditure-more-than-body-size-alone-predicts/Ali Araghi, MDen2026-10-06T15:08:22+00:00Weight loss lowers energy expenditure more than body size alone predictsChronic Obesity Biology, Adaptive Thermogenesishttps://aliaraghimd.org/2026/10/06/why-weight-comes-back-obesity-is-a-biologically-defended-state/Ali Araghi, MDen2026-10-06T15:08:19+00:00Why weight comes back: obesity is a biologically defended stateNutrition, Exercise Physiology, Chronic Obesity Biology, Adaptive Thermogenesishttps://aliaraghimd.org/2026/10/06/pap-adherence-problems-are-often-interface-and-pressure-problems-not-motivation-problems/Ali Araghi, MDen2026-10-06T14:38:42+00:00PAP adherence problems are often interface and pressure problems — not motivation problemsObstructive Sleep Apnea, PAP Therapy, PAP Adherencehttps://aliaraghimd.org/2026/10/06/a-negative-home-sleep-study-does-not-always-rule-out-osa/Ali Araghi, MDen2026-10-06T14:38:40+00:00A negative home sleep study does not always rule out OSAObstructive Sleep Apnea, Home Sleep Apnea Testinghttps://aliaraghimd.org/2026/10/06/a-normal-overall-ahi-can-hide-clinically-important-rem-predominant-osa/Ali Araghi, MDen2026-10-06T14:38:37+00:00A normal overall AHI can hide clinically important REM-predominant OSAObstructive Sleep Apnea, REM-Predominant OSAhttps://aliaraghimd.org/2026/10/06/osa-is-not-one-disease-it-is-a-collection-of-physiologic-failure-modes/Ali Araghi, MDen2026-10-06T14:38:35+00:00OSA is not one disease — it is a collection of physiologic failure modesObstructive Sleep Apnea, OSA Endotypeshttps://aliaraghimd.org/2026/10/06/a-plethoric-ivc-can-mean-congestion-without-proving-fluid-responsiveness/Ali Araghi, MDen2026-10-06T12:07:49+00:00A plethoric IVC can mean congestion without proving fluid responsivenessSepsis, Fluid Tolerance, VExUShttps://aliaraghimd.org/2026/10/06/passive-leg-raise-is-a-fluid-challenge-you-can-take-back/Ali Araghi, MDen2026-10-06T12:07:47+00:00Passive leg raise is a fluid challenge you can take backSepsis, Fluid Responsiveness, Passive Leg Raisehttps://aliaraghimd.org/2026/10/06/a-fluid-responder-can-still-be-the-wrong-patient-to-give-fluid/Ali Araghi, MDen2026-10-06T12:07:44+00:00A fluid responder can still be the wrong patient to give fluidSepsis, Fluid Responsiveness, Fluid Tolerancehttps://aliaraghimd.org/2026/10/06/in-sepsis-fluid-responsiveness-is-only-half-the-question/Ali Araghi, MDen2026-10-06T12:07:42+00:00In sepsis, fluid responsiveness is only half the questionSepsis, Fluid Responsiveness, Fluid Tolerance, Fluid Stewardshiphttps://aliaraghimd.org/2026/10/06/not-every-copd-exacerbation-needs-antibiotics/Ali Araghi, MDen2026-10-06T11:50:17+00:00Not every COPD exacerbation needs antibioticsCOPD, COPD Exacerbation, Antibiotic Stewardshiphttps://aliaraghimd.org/2026/10/06/blood-eosinophils-can-help-decide-when-ics-are-worth-the-risk/Ali Araghi, MDen2026-10-06T11:45:48+00:00Blood eosinophils can help decide when inhaled corticosteroids are worth the riskCOPD, Blood Eosinophilshttps://aliaraghimd.org/2026/10/06/hyperinflation-may-explain-dyspnea-better-than-fev1-alone/Ali Araghi, MDen2026-10-06T11:41:52+00:00Hyperinflation may explain dyspnea better than FEV₁ aloneMechanical Ventilation, COPDhttps://aliaraghimd.org/2026/10/06/copd-is-not-just-airflow-obstruction/Ali Araghi, MDen2026-10-06T11:38:11+00:00COPD is not just airflow obstructionPulmonary Function Testing, COPD